- Title
- Multi-dimensional gastrointestinal symptom severity index: validation of a brief GI symptom assessment tool
- Creator
- Crowell, Michael D.; Umar, Sarah B.; Lacy, Brian E.; Jones, Michael P.; DiBaise, John K.; Talley, Nicholas J.
- Relation
- Digestive Diseases and Sciences Vol. 60, Issue 8, p. 2270-2279
- Publisher Link
- http://dx.doi.org/10.1007/s10620-015-3647-3
- Publisher
- Springer
- Resource Type
- journal article
- Date
- 2015
- Description
- Few instruments have been developed and validated for the evaluation of multi-dimensional GI symptoms. The Gastrointestinal Symptoms Severity Index (GISSI), a multi-dimensional, self-report instrument, was designed as a brief measure of the frequency, severity, and bothersomeness of individual GI and pelvic floor/urogynecologic symptoms. Aim: To report the psychometric properties of the GISSI subscales, including factorial structure, validity, and internal consistency. Methods: The GISSI included 32 items that assessed upper and lower GI symptoms and seven items related to pelvic floor/urogynecologic symptoms. A total of 934 patients presenting for upper and lower GI complaints completed the questionnaire between January 2013 and December 2013. The sample was randomly split into derivation (n = 466) and validation datasets (n = 468). A non-patient sample of 200 was collected separately. Results: Exploratory factor analysis supported a six-factor model for the derivation sample that accounted for 69.3% of the total variance. The six GI symptom clusters were labeled as constipation/difficult defecation (five items), abdominal pain/discomfort (four items), dyspepsia (four items), diarrhea/anal incontinence (four items), GERD/chest symptoms (four items), and nausea/vomiting (two items). Inclusion of additional items related to female pelvic floor/urogynecologic symptoms resulted in a separate factor. Confirmatory factor analysis of the validation dataset supported the a priori hypothesized six-factor measurement model (X2(428) = 1462.98; P<0.001; GFI = .88; RMSEA = .051). Conclusion: The GISSI demonstrated good to excellent psychometric properties and provided multi-dimensional scaling of prominent GI symptom clusters. Further validation may provide an efficient, valid, and reliable measure of patient-reported clinical outcomes.
- Subject
- gastrointestinal symptoms severity index; psychometrics; gastrointestinal symptoms; urogynecologic symptoms; pelvic symptoms
- Identifier
- http://hdl.handle.net/1959.13/1338822
- Identifier
- uon:28111
- Identifier
- ISSN:0163-2116
- Language
- eng
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